Expression and Function of PDCD1 at the Human Maternal-Fetal Interface1
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چکیده
منابع مشابه
HLA Expression at the Maternal-Fetal Interface
Pregnancy in the human presents an "immunological paradox," because of the unexpected willingness of mothers to accept genetically disparate tissues. The fact that the fetus can develop unharmed for nine months shows that protective mechanisms must exist to permit its survival. The conditions that permit the genetically dissimilar human fetus to evade rejection by its mother's immune system hav...
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The present study was undertaken to examine serum parameters of thyroid function at term in normal pregnant women and their normal fetuses. Paired sera from 56 mothers and their respective newborn infants' umbilical cord were obtained at parturition. Maternal and fetal TSH, FT4, T4, FT3 and T3 levels were measured and the differences between these two groups were analysed. The levels of fetal s...
متن کاملMaternal and fetal thyroid function.
Conception is followed by a series of hormonal and metabolic changes that involve most maternal endocrine systems. With regard to thyroid metabolism, these include an increase in serum thyroxine-binding globulin and thyroid hormone concentrations, increased renal clearance of iodine, and increased production and turnover of thyroxine (T). Fetal and maternal thyroid physiology differ, but the sy...
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Embryo implantation and formation of a functional placenta are complex processes that require a plethora of regulatory molecules. In recent years, many of these mediators have been identified, often from studies in experimental animals. Furthermore, their expression patterns at the embryo-maternal interface in women have been characterized and provide clues to their potential actions. What has ...
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Rab proteins are a family of small GTPases involved in a variety of cellular processes. The Rab11 subfamily in particular directs key steps of intracellular functions involving vesicle trafficking of the endosomal recycling pathway. This Rab subfamily works through a series of effector proteins including the Rab11-FIPs (Rab11 Family-Interacting Proteins). While the Rab11 subfamily has been well...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2008
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod.107.066324